Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Sep 7;46(18):9289–9298. doi: 10.1093/nar/gky811

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 1. — (A) One-dimensional PTM maps of the E. coli (Ec), budding yeast (Saccharomyces cerevisiae, Sc) and human (Hs) rRNAs. The PTM sites were plotted against rRNA sequences aligned by the sequence homology (shown in Supplementary Table S9) obtained by using the Clustal Omega software (https://www.ebi.ac.uk/Tools/msa/clustalo/). The PTM sites are colored yellow (pseudouridine), red (2′-O-methylated nucleoside), and blue (base-modified nucleoside). (B) Three-dimensional PTM maps of the Ec, Sc, and Hs ribosomes. The PTM sites were assigned to the three-dimensional structure of the rRNAs obtained from 4YBB.pdb (for Ec), 3U5B.pdb (Sc) and 4UG0.pdb (Hs). The RNA backbone is shown as a ribbon, and PTM sites are colored as in (A).