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Coupled catabolism and anabolism in self-reproducing systems. (A) Schematic showing how catabolism in a self-reproducing system can process unusable raw material into usable substrates. (B) Autocatalytic synthesis of covalent RNA catalyst (WXYZ) from inactive RNA substrates (WXY and Z) using an anabolic autocatalytic process in the Azoarcus ribozyme system.
