Table 3.

Cox proportional hazard models for prognostic factors

	Univariate analysis		Multivariate analysis
	HR (95% CI)	P value	HR (95% CI)	P value
Age (≥60 vs. < 60)	0.987 (0.442–2.204)	0.974
Gender (female vs. male)	1.153 (0.538–2.472)	0.714
Tumour size (≥5 vs. < 5)	1.535 (0.737–3.198)	0.252
AFP (≥20 vs. < 20)	1.361 (0.679–2.729)	0.385
TNM stage (III+IV vs. I+II)	2.351 (1.127–4.902)	0.023*	2.753 (1.394–5.437)	0.004
HBV infection (Yes vs. No)	1.014 (0.468–2.199)	0.972
Cirrhosis (Yes vs. No)	3.643 (1.581–8.390)	0.002**	3.139 (1.540–6.399)	0.002**
Metastasis (Yes vs. No)	2.120 (1.028–4.369)	0.042*	2.521 (1.320–4.814)	0.005**
miR-766-3p (low vs. high)	3.699 (1.793–7.629)	< 0.001**	3.691 (1.815–7.506)	< 0.001*

^*Statistically significant (P < 0.05),

^**Statistically significant (P < 0.01).