Table 2.

Effect of the solvent on glucose dehydration.^[a]

Entry	Solvent	t [c]	Yield [%]
		[h]	LGO	LGA	HMF	Total[d]
1	H2O	6	0	0	6.9	6.9
2	BuOH	6	0	0	5.2	5.2
3	DMSO	5	0	trace	75.6	75.6
4	THF	6	6.7	3.4	8.5	18.6
5	dioxane	6	6.4	1.2	7.8	15.4
6	GVL	5	4.5	1.0	6.3	11.8
7	MIBK	5	5.2	3.7	6.8	15.7
8	THF/H2O[b]	6	trace	12.8	58.2	71.0
9	dioxane/H2O[b]	6	trace	8.6	37.5	46.1
10	GVL/H2O[b]	4.5	trace	11.4	44.5	55.9
11	MIBK/H2O[b]	5	trace	2.3	16.4	18.7
12	H2O‐NaCl	6	0	0	7.5	7.5
13	THF/H2O	6	trace	2.4	20.8	23.2

[a] Reaction conditions: glucose (0.1 g), [PzS]H₂PW (65 μmol), and solvent (12 mL) at 180 °C. [b] The volume ratio of the polar aprotic solvent to the water was 5:1 and NaCl (0.37 g) was added to water. [c] The reaction time for the maximum yield of HMF. [d] The total yield of LGA, LGO, and HMF.