Table 1.
Selected baseline characteristics by serum uric acid quintile (unit: mg/dL) by gender
| Characteristics | Men |
Women |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Q1 (<4.7) | Q2 (4.7-5.3) | Q3 (5.4-5.9) | Q4 (6.0-6.8) | Q5 (>6.8) | p-value | Q1 (<3.6) | Q2 (3.6-4.0) | Q3 (4.1-4.5) | Q4 (4.6-5.1) | Q5 (>5.1) | p-value | |
| Total (n) | 395 | 410 | 456 | 416 | 456 | 684 | 650 | 629 | 711 | 770 | ||
| CKD development | 46 (10.6) | 34 (7.7) | 33 (7.4) | 34 (8.7) | 54 (12.8) | <0.05 | 79 (9.9) | 49 (7.1) | 64 (10.6) | 71 (10.2) | 116 (17.5) | <0.001 |
| Age (y) | 63.72±8.56 | 62.30±8.72 | 61.07±9.05 | 60.64±8.84 | 59.66±9.14 | <0.001 | 60.29±9.38 | 59.20±9.29 | 59.45±9.52 | 58.91±9.19 | 60.32±8.33 | <0.01 |
| Follow-up time (mo) | 46.21±18.80 | 45.91±20.29 | 46.50±19.56 | 47.42±19.19 | 46.79±18.15 | NS | 47.37±19.01 | 47.10±19.35 | 47.20±19.40 | 46.77±18.91 | 46.40±18.35 | NS |
| Married | 374 (94.7) | 382 (93.2) | 440 (96.5) | 393 (94.5) | 432 (94.7) | NS | 519 (75.9) | 515 (79.2) | 482 (76.6) | 558 (78.5) | 593 (77.0) | NS |
| College or higher | 32 (8.1) | 31 (7.6) | 50 (11.0) | 40 (9.6) | 54 (11.8) | NS | 19 (2.8) | 24 (3.7) | 24 (3.8) | 36 (5.1) | 25 (3.2) | NS |
| Smoker | 129 (32.7) | 140 (34.1) | 129 (28.3) | 129 (31.0) | 147 (32.2) | NS | 10 (1.5) | 14 (2.1) | 14 (2.2) | 22 (3.1) | 23 (3.0) | NS |
| Alcohol consumer | 236 (59.7) | 261 (63.7) | 297 (65.1) | 285 (68.5) | 356 (78.1) | <0.001 | 198 (28.9) | 192 (29.5) | 183 (29.1) | 236 (33.2) | 266 (34.5) | <0.05 |
| Exercise | 121 (30.6) | 104 (25.4) | 147 (32.2) | 133 (32.0) | 147 (32.2) | NS | 171 (25.0) | 180 (27.7) | 179 (28.5) | 251 (35.3) | 257 (33.4) | <0.001 |
| HTN | 116 (29.4) | 124 (30.2) | 143 (31.4) | 139 (33.4) | 183 (40.1) | <0.01 | 198 (28.9) | 188 (28.9) | 192 (30.5) | 245 (34.5) | 353 (45.8) | <0.001 |
| DM | 79 (20.0) | 56 (13.7) | 59 (12.9) | 44 (10.6) | 50 (11.0) | <0.01 | 73 (10.7) | 49 (7.5) | 49 (7.8) | 59 (8.3) | 81 (10.5) | NS |
| BMI (kg/m²) | 22.98±2.80 | 23.54±2.81 | 24.05±2.92 | 24.46±2.88 | 25.01±2.90 | <0.001 | 23.72±3.05 | 24.01±3.08 | 24.48±3.01 | 24.76±3.07 | 25.71±3.23 | <0.001 |
| Tchl (mg/dL) | 186.97±32.56 | 189.45±34.26 | 188.36±32.27 | 195.93±36.59 | 198.19±35.82 | <0.001 | 198.95±36.58 | 200.52±34.15 | 203.48±35.01 | 205.08±35.70 | 212.68±36.08 | <0.001 |
| Tg (mg/dL) | 127.90±94.38 | 142.16±82.28 | 158.88±104.10 | 172.57±117.05 | 197.74±131.36 | <0.001 | 125.80±70.34 | 126.92±64.91 | 136.63±73.83 | 150.52±86.53 | 174.62±110.36 | <0.001 |
| HDL (mg/dL) | 45.55±11.59 | 44.59±11.18 | 43.55±11.80 | 42.81±10.90 | 42.21±9.73 | <0.001 | 46.80±9.95 | 47.02±10.12 | 45.90±10.39 | 44.83±10.00 | 43.20±9.26 | <0.001 |
| Glucose (mg/dL) | 108.79±44.05 | 105.03±29.43 | 103.73±24.52 | 102.60±22.64 | 101.72±16.85 | <0.01 | 99.40±24.72 | 96.17±16.97 | 96.20±16.40 | 96.54±17.08 | 100.13±16.97 | <0.001 |
| eGFR (mL/min/1.73 m2) | 80.26±10.02 | 79.13±9.22 | 78.40±9.78 | 77.20±8.76 | 75.25±9.40 | <0.001 | 79.26±10.14 | 78.43±9.40 | 76.47±8.95 | 75.37±8.89 | 73.04±8.50 | <0.001 |
Values are presented as number (%) or mean±standard deviation.
CKD, chronic kidney disease; NS, not significant; HTN, hypertension; DM, diabetes mellitus; BMI, body mass index; Tchl, total cholesterol; Tg, triacylglycerol; HDL, high-density lipoprotein; eGFR, estimated glomerular filtration rate.