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. 2018 Aug 31;45(12):2181–2189. doi: 10.1007/s00259-018-4122-0

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 3 — Regional coronary uptake of ¹⁸F-NaF. A 64-year-old woman with unstable angina. (a), X-ray coronary angiogram of showed severe coronary stenosis at proximal (I) and mid (II) segments of LAD; Cardiac CT (b) and ¹⁸F-NaF PET/CT (c) showed regional distribution of ¹⁸F-NaF uptake within an atheromatous lesion. Representative LAD lesions showed distinct tracer accumulation along a severely fibrocalcific lesion. Prominent focal ¹⁸F-NaF uptake were observed at coronary segment I verse absent focal uptake at segment II. Anatomical IVUS indicate the presence of fibroatheromatous lesion with prominently increased necrotic (35% vs. 23%) and calcified tissue (10% vs. 6%) also a slightly higher proportion of lipidic tissue (9% vs.8%), but decreased fibrotic tissue (46 vs 62%) in segment I (d) in comparison to segment II (e)