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. 2018 Jul 23;67(10):1519–1531. doi: 10.1007/s00262-018-2211-3

Fig. 2.

Fig. 2

Phenotype of ovarian TIL. Ovarian TILs were stained with CD3, CD4, CD8 and markers associated with T cell differentiation. a The proportion of CD4+ and CD8+ lymphocytes in the expanded TIL populations. b Comparison of proportion of CD4+ and CD8+ lymphocytes in TILs expanded from biopsies taken at primary surgery and following neoadjuvant chemotherapy. c Heterogeneity of CD4:CD8 ratio in TILs expanded from biopsies from different anatomical sites. d Comparison of CD27 and CD28 expression between CD4+ and CD8+ T cells. e Expression of other T-cell differentiation markers on CD8+ and CD4+ (f) cells. Data are reported as mean % ± SD. **p < 0.01, unpaired Student’s t test