Table 1.
Study characteristics
Study | Year | Germline mutation or Amsterdam only | Total cases | Gender (male %) | Mean follow-up | Mean age diagnosis | Range of age of diagnosis | Segmental Colectomy | MCC after Segmental colectomy | Extended colectomy | MCC after Extended colectomy |
---|---|---|---|---|---|---|---|---|---|---|---|
Kalady [34] | 2012 | Amsterdam | 296 | 47.9 | 104 | 47.9 | – | 253 | 55 | 43 | 3 |
Van Dalen [35] | 2003 | Amsterdam | 93 | n/a | 156 | 47 | 26–81 | 70 | 16 | 23 | 0 |
Cirillo [32] | 2013 | Amsterdam | 65 | 58.5 | 72 | 47 | – | 54 | 15 | 11 | 2 |
Vasen [36] | 1993 | Amsterdam | 54 | n/a | 69.6 | 45 | 17–88 | 37 | 8 | 17 | 2 |
Parry [13] | 2011 | Germline | 382 | 51 | 108 | 46 | – | 332 | 74 | 50 | 0 |
Cappel [37] | 2002 | Germline | 139 | n/a | 81.6 | 46 | 24–78 | 110 | 13 | 29 | 1 |
Natarajan [38] | 2010 | Germline | 106 | 39.6 | 144 | 45.5 | – | 69 | 23 | 37 | 4 |
Kim [39] | 2017 | Germline | 106 | 52.8 | 68.1 | 43.5 | 24–82 | 76 | 13 | 30 | 0 |
Win [25] | 2013 | Germline | 88 | 44 | 132 | 42.8 | – | 79 | 21 | 9 | 0 |
Stupart [28] | 2011 | Germline | 60 | 59.2 | 72 | 44 | – | 39 | 8 | 21 | 0 |