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. 2018 Jul 27;235(10):2897–2913. doi: 10.1007/s00213-018-4980-y

Table 2.

The subthreshold doses of LSP4-2022 and VU152100 administered in each test

Test LSP4-2022 VU152100
MK-801-induced hyperactivity 0.1 mg/kg 5 mg/kg
DOI-induced head twitches 0.5 mg/kg 1 mg/kg
Modified forced swim test 0.1 mg/kg 0.1 mg/kg
Social interaction 0.1 and 0.5 mg/kg 2 and 5 mg/kg
Novel object recognition 1 mg/kg 0.25 mg/kg
Amphetamine-induced hyperactivity and PET studies (rats) 0.1 mg/kg 5 mg/kg