Table 3.

Control experiments for the most active doses of VU152100 and combinations of LSP4-2022+VU152100 in behavioral studies

	Locomotor activity of habituated animals (ambulation counts)	Social interaction (time of interaction in s)	Novel object recognition (recognition index)	Modified forced swim test (ambulation counts)
Control	1100 ± 100	18.1 ± 1.9	0.35 ± 0.03	1308 ± 112
VU152100 (5 mg/kg)	1050 ± 142 ns	19.14 ± 1.9 n.s
VU152100 (2 mg/kg) + LSP4 (0.1 mg/kg)		19.43 ± 1.02 n.s
VU152100 (1 mg/kg)			0.28 ± 0.02
VU152100 (0.25 mg/kg) + LSP4 (0.1 mg/kg)			0.36 ± 0.02
VU152100 (2 mg/kg)				1262 ± 157 ns
VU152100 (0.1 mg/kg) + LSP4 (0.1 mg/kg)				1203 ± 110 ns
VU152100 (5 mg/kg) + LSP4 (0.1 mg/kg)	993 ± 95 ns

The table shows the effects of the two activators in the absence of MK-801 for the corresponding behavioral tests. Number of animals in each group n = 8