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. 2018 Sep 12;35(10):1564–1577. doi: 10.1007/s12325-018-0784-z

Table 3.

Frequency of most common adverse events (> 10% of total cases) by first-line therapy group

Total 1L therapy P value
N = 654 (%) nab-P + G (%) FFX (%)
Anemia 45.43 45.50 45.34 0.98
Febrile neutropenia 12.49 9.21 16.23 0.07
Neutropenia 32.73 33.38 31.99 0.79
Thrombocytopenia 24.97 27.11 22.52 0.34
Diarrhea 29.46 20.51 39.71 < 0.001*
Stomatitis 10.10 3.62 17.52 < 0.001*
Abdominal pain 19.48 21.18 17.54 0.38
Alopecia 16.45 16.34 16.57 0.96
Decreased appetite 27.79 25.81 30.06 0.39
Dehydration 18.54 14.93 22.67 0.08
Fatigue 37.28 31.80 43.56 < 0.05*
Mucositis 11.37 5.16 18.48 < 0.001*
Nausea and vomiting 23.25 18.27 28.94 < 0.05*

FFX FOLFIRINOX, nab-P + G nanoparticle albumin-bound paclitaxel/gemcitabine, 1L first-line

*P < 0.05