Table 2.
Odd ratios for live birth in DOR women undergoing IVF-ET
| Crude OR (95% CI) | P value | Adjusted OR (95% CI) | Adjusted P value | |
|---|---|---|---|---|
| Maternal age (years) | ||||
| ≤ 30 | Reference | Reference | ||
| 31–34 | 0.80 (0.62–1.03) | 0.083 | 0.87 (0.60–1.25) | 0.442 |
| 35–39 | 0.60 (0.46–0.78) | < 0.001 | 0.74 (0.46–1.18) | 0.203 |
| ≥ 40 | 0.23 (0.16–0.32) | < 0.001 | 0.26 (0.14–0.47) | < 0.001 |
| Body mass index (kg/m2) | 0.96 (0.93–1.00) | 0.039 | 1.02 (0.97–1.06) | 0.461 |
| Duration of infertility (years) | 0.95 (0.93–0.98) | < 0.001 | 0.99 (0.95–1.03) | 0.542 |
| Paternal age (years) | 0.94 (0.92–0.96) | < 0.001 | 0.98 (0.95–1.01) | 0.188 |
| Total gonadotropin dose (IU) | 0.92 (0.84–1.01) | 0.064 | 0.92 (0.81–1.04) | 0.167 |
| Endometrial thickness on day of hCG (mm) | 1.06 (1.01–1.10) | 0.021 | 1.03 (0.97–1.09) | 0.322 |
| Number of follicles ≥ 14 mm (n) | 1.04 (1.01–1.07) | 0.009 | 0.97 (0.92–1.03) | 0.382 |
| Number of oocytes retrieved (n) | 1.05 (1.03–1.07) | < 0.001 | 0.98 (0.93–1.04) | 0.540 |
| First IVF cycle (n) | 1.39 (1.11–1.75) | 0.004 | 1.30 (0.94–1.79) | 0.109 |
| Poor ovarian response (n) | 0.46 (0.34–0.61) | < 0.001 | 0.91 (0.57–1.44) | 0.686 |
| Number of frozen embryos (n) | 1.08 (1.02–1.15) | 0.010 | 1.09 (1.00–1.18) | 0.060 |
| Embryo stage (n) | ||||
| Day 2 | Reference | Reference | ||
| Day 3 | 1.98 (1.58–2.48) | < 0.001 | 1.53 (1.13–2.08) | 0.006 |
| Number of embryos transferred (n) | ||||
| One | Reference | Reference | ||
| Two | 3.41 (2.45–4.74) | < 0.001 | 2.53 (1.62–3.97) | < 0.001 |
| Three | 2.97 (2.10–4.21) | < 0.001 | 4.59 (2.73–7.70) | < 0.001 |
Multivariate logistic regression analysis was conducted accounting for potential confounders within the cycles performed in our center
OR odds ratio, CI confidence interval, DOR diminished ovarian reserve, IVF-ET in vitro fertilization and embryo transfer, hCG human chorionic gonadotropin