Table 2.

Parameter estimates from best linear mixed effect models For L-PZQ AUC in Healthy volunteers enrolled in studies 200585-001 and 200661-001

Study	Parameter	Estimate	Standard error	T test	p value
200585-001	Intercept	− 9.99	0.850	− 11.76	< 0.0001
	Ln-DOSE	2.30	0.116	19.9	< 0.0001
	Food	0.811	0.0956	8.49	< 0.0001
	Var(Intercept)	0.209
	Residual Variance	0.0972
200661-001	Intercept	− 7.52	0.930	− 8.09	< 0.0001
	Ln-DOSE	2.01	0.126	15.98	< 0.0001
	ODT formulation	− 0.81	0.0746	− 10.85	< 0.0001
	Food	0.62	0.0754	8.17	< 0.0001
	Var(Intercept)	0.372
	Residual Variance	0.148