Figure 1.
Effects of EE and MPTP on the average escape latency of SAMP8 mice in the place navigation test of the Morris water maze task.
Data are shown as the mean ± SD (two-way repeated measures analysis of variance followed by the least significant difference post hoc test). **P < 0.01, vs. SE + NS group; ##P < 0.01, vs. EE + NS group; ††P < 0.01, vs. SE + MPTP group. EE: Enriched environment; SE: standard environment; MPTP: 1-methyl-4-phenyl-1,,2,3,6-tetrahydropyridine; NS: normal saline; SAMP8: senescence-accelerated mouse prone 8.