Fig. 4.
Fractional release of siRNA-NP from hydrogels increases as a function of overall hydrogel degradability. *, #, and $ indicates significant difference between nondegradable and 100%, 50% and 20% degradable hydrogels, respectively. & indicates significant difference between 20% and 100% degradable hydrogels. (p<0.05, N=4, mean ± standard deviation. 2- way ANOVA with Tukey’s post hoc analysis).