Table 1.

Description of past and present pneumococcal vaccines. Table was adapted from references 4 and 9.

Vaccine	Year Introduced	Carrier Protein	Serotypes	Impacts
PSV23	1983	N/A	1,2,3,4,5,6B,7F,8,9N,9V,10A,11A,12F,14,15B	-Reduced invasive disease in adults
			17F,18C,19A,19F,20,22F,23F,and33F	-Not protective in children
PCV7	2000	CRM197	4,6B,9V,14,18C,19F, and 23F	-Reduced invasive disease
				-More protective in children
				-Increase 19A and 7F infections
PCV10	2011 (Not in US)	NTHi protein D; tetanus toxoid; diphtheria toxoid	1,4,5,6B,7F,9V,14,18C,19F, and 23F	-Decrease in otitis media infection
PCV13	2010	CRM197	1,3,4,5,6A,6B,7F,9V,14,18C,19A,19F, and 23F	-Reduced invasive disease-Protection in all age/risk groups-Increase in 35B infections