Table 1.
Demographics and baseline characteristics of participants by age group and treatment.
| Placebo | ExPEC4V |
|||
|---|---|---|---|---|
| N = 12 | 4:4:4:4 N = 12 | 8:8:8:8 N = 12 | 16:16:16:16 N = 12 | |
| All ages | ||||
| Sex, n (%) | ||||
| Male | 5 (42) | 6(50) | 6(50) | 5 (42) |
| Race, n (%) | ||||
| Asian | 12 (100) | 12 (100) | 12 (100) | 12 (100) |
| Age (years) | ||||
| Mean (SD) | 44.2 (16.57) | 44.6 (15.48) | 45.6 (10.97) | 51.9 (13.83) |
| Body-mass index (kg/m2) | ||||
| Mean (SD) | 22.94 (2.374) | 22.10 (1.817) | 22.17 (2.575) | 22.22 (2.832) |
| Childbearing potential for female patients, n (%) | ||||
| N | 7 | 6 | 6 | 7 |
| Yes | 4 (57) | 4 (67) | 3 (50) | 3 (43) |
| Cigarette smokers, n (%) | ||||
| N | 5 | 6 | 8 | 9 |
| Current | 1 (20) | 2 (33) | 3 (38) | 5 (56) |
| Former | 4 (80) | 4 (67) | 5 (63) | 4 (44) |
| Age: > = 20 to <50 years | ||||
| N | 6 | 6 | 6 | 6 |
| Sex, n (%) | ||||
| Male | 2 (33) | 3 (50) | 4 (67) | 3 (50) |
| Age (years) | ||||
| Mean (SD) | 30.3 (9.91) | 32.7 (13.11) | 37.3 (9.22) | 41.0 (9.17) |
| Body-mass index (kg/m2) | ||||
| Mean (SD) | 23.05 (3.078) | 21.77 (2.067) | 21.44 (3.120) | 21.16 (2.643) |
| Childbearing potential for female patients, n (%) | ||||
| N | 4 | 3 | 2 | 3 |
| Yes | 4 (100) | 3 (100) | 2 (100) | 3 (100) |
| Cigarette smokers, n (%) | ||||
| N | 2 | 3 | 6 | 5 |
| Current | 1 (50) | 1 (33) | 2 (33) | 4 (80) |
| Former | 1 (50) | 2 (67) | 4 (67) | 1 (20) |
| Age: > = 50 years | ||||
| N | 6 | 6 | 6 | 6 |
| Sex, n (%) | ||||
| Male | 3 (50) | 3 (50) | 2 (33) | 2 (33) |
| Age (years) | ||||
| Mean (SD) | 58.0 (6.84) | 56.5 (3.83) | 53.8 (4.07) | 62.8 (7.14) |
| Body-mass index (kg/m2) | ||||
| Mean (SD) | 22.83 (1.702) | 22.43 (1.651) | 22.91 (1.886) | 23.29 (2.815) |
| Childbearing potential for female patients, n (%) | ||||
| N | 3 | 3 | 4 | 4 |
| Yes | 0 | 1 (33) | 1 (25) | 0 |
| Cigarette smokers, n (%) | ||||
| N | 3 | 3 | 2 | 4 |
| Current | 0 | 1 (33) | 1 (50) | 1 (25) |
| Former | 3 (100) | 2 (67) | 1 (50) | 3 (75) |