Pedigree of patient with SCA12. Arrow indicates our patient (III:1). Shaded symbols represent affected individuals. Based on history, II:1 had gait impairment, hand tremor, anxiety, dementia, and died in her eighties, II:3 had gait impairment, dementia, and died in her seventies, and I:2 had gait impairment, anxiety, possible hand tremor, and died in her seventies. Unshaded symbols represent unaffected individuals.