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Long-lasting antigen-specific memory B and plasma cell responses. (A and B) Pd-specific IgA- and IgG-secreting plasma cells from bone morrow, respectively, and (C, D) IgA- and IgG-secreting memory B cells from spleen at two weeks after the final vaccination. The results are presented as the mean ± SEM, and statistical significance was determined by Student's t-test: * p<0.05; ** p<0.01; *** p<0.001; NS, not significant, and ND, not detected.
