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. 2018 Oct 5;9:2287. doi: 10.3389/fimmu.2018.02287

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Copyright © 2018 Shen, Luo, Wu, Huang, Xiao, Wang, Yang, Li and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CD8⁺ T cells localized in B cell follicles in tonsils and lymph nodes express CXCR5. The expression of CXCR5 on CD8 T cells in tonsils, lymph nodes and PBMCs was shown in the representative histogram graphs (A) and summary data (B, n = 8). Immunofluorescence staining of CD3⁺ T cells (green) and CD8⁺ T cells (red) (C, n = 5), CD8⁺ T cells (green) and CXCR5 (red) (D, n = 5) in paraffin-embedded tonsil tissues. Data are expressed as the mean ± SD, and compared with Mann-Whitney test. *P < 0.05, **P < 0.01, and ***P < 0.001.