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. 2018 Oct 8;13:3131–3139. doi: 10.2147/COPD.S171134

Table 4.

Patients’ percentage of change of ultrasonographic measurements after pulmonary rehabilitation between “markedly improved” and “slightly improved” patients based on MCID at 6MWT

Ultrasonographic measurements 6MWD >54 m N=8 6MWD <54 m N=17 P-value




Diaphragm zapp
 ΔLzapp TLC% −15 (−26 to −12) −18 (−23 to −9) 0.791
 ΔLzapp FRC% 12 (10–15) 8 (3–11) 0.023
 ΔSzapp TLC% −5 (−8 to −2) −5 (−10 to −3) 0.733
 ΔSzapp FRC% −6 (−9 to 0) −7 (−11 to 0) 0.850
Diaphragmatic excursion
 ΔQuiet breathing, % 5 (2–10) 15 (3–44) 0.112
 ΔDeep breathing, % 6 (1–12) 17 (5–47) 0.132
ΔRectus femoris area, % 10 (6–15) 8 (4–12) 0.850

Note: Data are presented as median (25th–75th percentiles).

Abbreviations: MCID, minimally clinical important difference; PR, pulmonary rehabilitation; zapp, diaphragm zone of apposition; Lzapp, length of diaphragm zone of apposition; Szapp, thickness of diaphragm zone of apposition; TLC, total lung capacity; FRC, functional residual capacity; 6MWD, 6-minute walking distance; 6MWT, 6-minute walking test.