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. 2018 Oct 8;10:4311–4323. doi: 10.2147/CMAR.S173496

Figure 5.

Figure 5

Deregulation of signaling pathways upon knockdown of NUDT21.

Notes: (A) Heatmap of 697 differentially expressed genes after knockdown of NUDT21 in K562 cells. (B) Enrichment analysis of differentially expressed genes in GO terms. (C) Enrichment analysis of differentially expressed genes in KEGG pathways. (D) The histogram showing the relative protein expressions of the key signaling components in K562 cells after transfection of shRNA control or NUDT21 shRNA. Data are expressed as mean ± SD for duplicate experiments.

Abbreviations: GO, gene ontology; KEGG, Kyoto Encyclopedia of Genes and Genomics.