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. 2018 Sep 6;7:e38841. doi: 10.7554/eLife.38841

Figure 2. The RF surround regulates nonlinear spatial integration of natural images.

(A) We presented a natural image patch and its linear-equivalent disc stimulus to probe sensitivity to spatial contrast in natural scenes. Rows of each raster correspond to repeated presentations of the same stimulus for the example Off parasol RGC. (B) Spike count responses to an example image patch and its linear equivalent disc across a range of surround contrasts. The addition of a sufficiently bright surround (top three points) eliminates sensitivity to spatial contrast in this image patch. (C) Population summary showing the response difference between image and disc as a function of the difference in mean intensity between the RF center and surround. Negative values of this difference correspond to a surround that is brighter than the center, and positive values to a surround that is darker than the center (n = 21 image patch responses measured in five Off parasol RGCs).

Figure 2—source data 1. Included is a .mat file containing a data structure for the data in Figure 2.
Individual trial responses are included as binary vectors of spike times for natural image and associated linear equivalent disc stimuli, across a range of surround contrast conditions. Data are organized by cell and then by natural image. The natural image used in each set of responses is also included. For all responses, data are sampled at 10 Khz, and both center and surround stimuli appear after 200 ms and persist for 200 ms.
elife-38841-fig2-data1.mat (168KB, mat)
DOI: 10.7554/eLife.38841.005

Figure 2.

Figure 2—figure supplement 1. Measuring linear center-surround structure in parasol RGCs.

Figure 2—figure supplement 1.

(A) Off parasol RGC spike responses to expanding spots stimuli. (B) Area-summation curve from the cell in (A), points show mean ± S.E.M., smooth curve is a difference-of-Gaussians fit. (C–D) Same as (A–B) for excitatory current responses.