Table 2:
Participant Characteristics from USA and Danish Data Sets
| USA | Denmark | Significance | |
|---|---|---|---|
| Female, No. | 267 | 187 | |
| Age, mean ± SD, y | 36 ± 11.6 | 36 ± 12.6 | ns |
| Race/ethnicity, No. (%) | |||
| White | 264 (99) | 187 (100) | |
| Black | 3 (1) | ||
| Hispanic | 0 | ||
| Asian | 0 | ns | |
| Ulcerative colitis, No. (%) | 82 (34.0) | 74 (39.8) | |
| Crohn’s disease, No. (%) | 159 (66.0) | 112 (60.2) | ns |
| Montreal classification | |||
| Crohn’s disease behavior, No. (%) | |||
| B1: Inflammatory | 67 (42.2) | 59 (52.7) | |
| B2: Stricturing | 27 (16.9) | 23 (20.5) | |
| B3: Penetrating | 24 (14.9) | 11 (9.8) | |
| B4: Perianal disease | 41 (26.0) | 19 (17.0) | |
| Crohn’s disease location, No. (%) | |||
| L1: Ileal | 37 (23.2) | 14 (12.5) | |
| L2: Ileocolonic | 25 (15.5) | 34 (30.4) | |
| L3: Colonic | 91 (57.4) | 63 (56.3) | |
| L4: Upper tract | 6 (3.9) | 1 (0.8) | |
| Ulcerative colitis disease extent, No. (%) | |||
| E1: Limited to the rectum | 10 (12.0) | 19 (21.4) | |
| E2: Left sided (colorectum distal to splenic flexure) | 22 (26.7) | 23 (32.9) | |
| E3: Extensive (proximal to splenic flexure) | 50 (61.3) | 32 (45.7) | |
| Age at diagnosis, No. (%) | |||
| <40 y | 182 (68.0) | 132 (70.6) | |
| 40–59 y | 66 (24.8) | 42 (22.3) | |
| ≥60 y | 19 (7.2) | 13 (7.1) | ns |
| Presence of stoma, No. (%) | 20 (7.5) | 10 (5.4) | ns |
| Prior IBD surgery, No. (%) | 104 (39.1) | 48 (25.9) | <0.001 |
| IPAA, No. (%) | 13 (4.9) | 4 (2.1) | <0.001 |
| Current medications, No. (%) | <0.001 | ||
| Corticosteroids | 30 (11.3) | 20 (10.7) | 0.835 |
| Immunomodulators | 65 (24.2) | 97 (51.8) | <0.001 |
| Anti-TNF alpha | 124 (46.4) | 102 (54.6) | 0.089 |
| Anti IL12/23 | 19 (7.2) | 5 (2.7) | 0.036 |
| Narcotics | 22 (8.3) | 29 (15.5) | <0.001 |
| Marital status, No. (%) | |||
| Single | 69 (25.8) | 42 (22.6) | |
| Married/living together | 179 (63.5) | 122 (65.1) | |
| Divorced/separated | 28 (10.4) | 20 (10.7) | ns |
| Female scores, mean ± SD | |||
| FSFI | 46.3 ± 17.1 | 46.0 ± 18.3 | ns |
| FSDS-R | 13.0 ± 11.7 | 14.9 ± 11.5 | ns |
| PHQ-9 score, No. (%) | |||
| Minimal | 148 (55.3) | 61 (32.8) | |
| Mild | 79 (29.5) | 66 (35.5) | |
| Moderate | 31 (11.5) | 37 (19.9) | |
| Moderately severe | 6 (2.5) | 19 (10.2) | |
| Severe | 3 (1.2) | 3 (1.6) | <0.001 |
| Active IBD cases, No. (%) | |||
| Harvey-Bradshaw Index, score ≥5 | 45 (28.4) | 33 (29.7) | ns |
| SCCAI, score ≥5 | 18 (21.8) | 25 (33.3) | <0.001 |