Figure 3.

Tafa-2^−/− mice displayed increased level of anxiety-like behaviors (A,B) Open-field test (n = 11 for each genotype). Total distance traveled (A) and time spent in the central zone (B) were compared between wt and Tafa-2^−/− mice. (C–F) Elevated plus maze test (n = 10 for each genotype). Time spent in open arms (C), distance traveled in open arms expressed as percentage values of total distance (D), number of entries to the open and closed arms (E) and total distance traveled (F) were compared between wt and Tafa-2^−/− mice. Data are shown as the mean ± SE. Student’s t test: *P < 0.05, **P < 0.01.