Table 3. Factors associated with chaotrope-based anti-Ag85A antibody avidity e.
| Factor | Adjusted GMR (95%CI) f | P value | Q value g |
|---|---|---|---|
| Age | 1.000 (0.993–1.007) | 0.978 | |
| Gender | |||
| Female | 1 | ||
| Male | 0.861 (0.722–1.027) | 0.098 | |
| HIV serostatus | |||
| Negative | 1 | ||
| Positive | 0.677 (0.567–0.812) | <0.001 | |
| SES | |||
| Low | 1 | ||
| Medium | 1.317 (1.052–1.649) | 0.016 | |
| M.tb infection state | |||
| Uninfected | 1 | ||
| LTBI | 1.024 (0.738–1.419) | 0.889 | 1.000 |
| APTB | 1.641 (1.153–2.337) | 0.006 | 0.018 |
| APTB Vs LTBI† | 1.604 (1.282–2.006) | <0.001 | <0.001 |
GMR: geometric mean ratio, LTBI: latent tuberculosis infection, APTB: active pulmonary tuberculosis, SES: socioeconomic status.
e 9 uninfected controls, 11 LTBI and 48 APTB cases.
f Results were generated using linear regression and the factors were adjusted for one another.
g Q values were computed for multiple comparisons between M.tb infection states and uninfected controls using the Bonferroni method.
† LTBI is baseline comparison group.
Crude GMRs can be found in S2 Table in the supporting information.