Table 4. Factors associated with anti-Ag85A antibody responses determined by SPR h.
Factor | Adjusted GMR (95%CI) i | P value | Q value j |
---|---|---|---|
Age | 0.996 (0.990–1.001) | 0.128 | |
Gender | |||
Female | 1 | ||
Male | 1.004 (0.844–1.195) | 0.962 | |
HIV serostatus | |||
Negative | 1 | ||
Positive | 0.983 (0.764–1.263) | 0.892 | |
SES | |||
Low | 1 | ||
Medium | 1.076 (0.908–1.275) | 0.398 | |
M.tb infection state | |||
Uninfected | 1 | ||
LTBI | 1.213 (1.007–1.459) | 0.041 | 0.123 |
APTB | 1.446 (1.151–1.817) | 0.002 | 0.006 |
APTB Vs LTBI¢ | 1.192 (0.970–1.466) | 0.095 | 0.285 |
GMR: geometric mean ratio, LTBI: latent tuberculosis infection, APTB: active pulmonary tuberculosis, SES: socioeconomic status.
h 23 uninfected controls, 24 LTBI and 34 APTB cases.
i Results were generated using linear regression and the factors were adjusted for one another.
j Q values were computed for multiple comparisons between M.tb infection states and uninfected controls using the Bonferroni method.
¢ LTBI is baseline comparison group.
Crude GMRs can be found in S3 Table in the supporting information.