Table 2. 17 loci with evidence for G × S interactions.
| Locus | SNP | Chrom. | Nuc. Position (hg19) |
Closest Gene |
A1 | A2 | MAF | P.2df | P.G×S |
|---|---|---|---|---|---|---|---|---|---|
| 3p24.3 | rs12490991 | 3 | 16457095 | RFTN1 | A | G | 0.308 | 1.85E-05 | 3.66E-06 |
| 5p13.1 | rs72753006 | 5 | 42310935 | GHR | C | G | 0.080 | 1.53E-05 | 2.70E-06 |
| 5q31.3 | rs34993514 | 5 | 139651948 | PFDN1 | A | AT | 0.425 | 3.46E-05 | 7.25E-06 |
| 6q26 | rs6932653 | 6 | 163666803 | PACRG | C | C | 0.425 | 1.26E-05 | 3.74E-06 |
| 8p23.2 | rs2623571 | 8 | 3572809 | CSMD1 | T | T | 0.109 | 2.75E-05 | 4.72E-06 |
| 9p24.1 | rs148091490 | 9 | 4950144 | JAK2 | C | T | 0.079 | 1.89E-05 | 3.22E-06 |
| 9q21.32 | rs1246259 | 9 | 86766132 | SLC28A3 | A | G | 0.328 | 1.20E-05 | 2.39E-06 |
| 9q22.1 | rs11142081* | 9 | 90689210 | SPATA31C2 | T | G | 0.137 | 2.09E-06 | 6.29E-07 |
| 10q21.1a | rs370068281 | 10 | 55079463 | PCHD15 | ATG | A | 0.165 | 1.28E-05 | 2.06E-06 |
| 10q21.1b | rs72804706 | 10 | 59564480 | IPMK | C | T | 0.102 | 3.67E-08 | 6.69E-09 |
| 13q13.3 | rs77590619 | 13 | 36148527 | NBEA | G | A | 0.256 | 4.78E-06 | 7.72E-07 |
| 13q21.33 | rs17087328 | 13 | 71141833 | LINC00438 | T | C | 0.089 | 4.39E-05 | 8.23E-06 |
| 13q31.3 | rs28793707 | 13 | 86486416 | SLITRK6 | T | C | 0.163 | 1.64E-05 | 3.20E-06 |
| 15q26.1 | rs11855106 | 15 | 93599565 | RGMA | G | A | 0.376 | 4.24E-05 | 9.59E-06 |
| 17q21.31 | -- | 17 | 42535623 | GPATCH8 | GA | G | 0.106 | 2.57E-05 | 6.76E-06 |
| 17q25.1 | rs4479318 | 17 | 70906038 | SLC39A11 | T | T | 0.481 | 2.74E-05 | 5.54E-06 |
| 19p13.3 | rs7247005 | 19 | 3416299 | NFIC | G | A | 0.221 | 1.41E-05 | 3.81E-06 |
*
indicates genotyped SNPs, others are imputed