Table 2.
Proteins detected by mass spectrometry in significantly different abundance between mucoid and serous MEEs.
| Uniprot ID | description | Serous/Mucoid | Mucoid/Serous |
|---|---|---|---|
| P35579 | Myosin-9 | 0.02 | 48.64 |
| P05164 | Myeloperoxidase | 0.03 | 37.85 |
| P13796 | Plastin-2 | 0.03 | 34.32 |
| P04040 | Catalase | 0.04 | 27.44 |
| P06744 | Glucose-6-phosphate isomerase | 0.04 | 27.33 |
| P07437 | Tubulin beta chain | 0.05 | 19.44 |
| Q9HC84 | Mucin-5B | 0.06 | 18.11 |
| P08246 | Neutrophil elastase | 0.06 | 17.54 |
| P41218 | Myeloid cell nuclear differentiation antigen | 0.06 | 16.25 |
| Q9BQE3 | Tubulin alpha-1C chain | 0.07 | 15.36 |
| Q8TDL5 | BPI fold-containing family B member 1 | 0.07 | 15.23 |
| P40199 | Carcinoembryonic antigen-related cell adhesion molecule 6 | 0.07 | 13.88 |
| P11142 | Heat shock cognate 71 kDa protein | 0.08 | 12.00 |
| P02788 | Lactotransferrin | 0.09 | 11.23 |
| P40121 | Macrophage-capping protein | 0.09 | 10.86 |
| P80188 | Neutrophil gelatinase-associated lipocalin | 0.26 | 3.89 |
| P04004 | Vitronectin | 0.32 | 3.10 |
| P05109 | Protein S100-A8 | 0.35 | 2.88 |
| P07195 | L-lactate dehydrogenase B chain | 0.37 | 2.74 |
| P30041 | Peroxiredoxin-6 | 0.40 | 2.50 |
| P04207 | Ig kappa chain V-III region CLL | 0.40 | 2.48 |
| P06396 | Gelsolin | 0.42 | 2.38 |
| P00751 | Complement factor B | 0.43 | 2.35 |
| P0CG05 | Ig lambda-2 chain C regions | 0.49 | 2.04 |
| P08185 | Corticosteroid-binding globulin | 0.49 | 2.04 |
| P02675 | Fibrinogen beta chain | 0.50 | 2.00 |
| P00747 | Plasminogen | 2.04 | 0.49 |
| P04003 | C4b-binding protein alpha chain | 2.06 | 0.48 |
| P13671 | Complement component C6 | 2.17 | 0.46 |
| P43652 | Afamin | 2.39 | 0.42 |
| P10643 | Complement component C7 | 2.96 | 0.34 |
| P55058 | Phospholipid transfer protein | 3.00 | 0.33 |
| P51884 | Lumican | 3.15 | 0.32 |
| P41222 | Prostaglandin-H2 D-isomerase | 3.67 | 0.27 |
| P01031 | Complement C5 | 4.05 | 0.25 |
| P06727 | Apolipoprotein A-IV | 5.08 | 0.20 |
| P02656 | Apolipoprotein C-III | 5.50 | 0.18 |
Peptide counts of the datasets were normalized to the total peptide count for each sample. These normalized datasets were subjected to a Wilcoxon rank sum test to compare the abundance of proteins between mucoid vs serous groups, with proteins detected in at least 2 samples per group. All the proteins listed are significantly different between mucoid and serous samples with an unadjusted p-value < 0.05. Fold inductions were calculated by dividing the average proportion in the two groups.