Carotid artery occlusion was induced in wild type C57Bl/6 mice (WT, white bars), and in mice lacking factor IX (FIX−/−, black), factor XI (FXI−/−, green), factor XII (XII−/−, blue), prekallikrein (PK−/−, yellow), or high molecular weight kininogen (HK−/−, red) by exposing the vessel to varying concentrations of FeCl3 (as indicated at the bottom of the graph) for three minutes. The percent of animals with patent arteries 30 minutes after FeCl3 exposure is shown (n = 10 for each bar).