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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Mol Aspects Med. 2018 Apr 12;64:79–91. doi: 10.1016/j.mam.2018.04.001

Figure 4. Potential molecular mechanism of metabolic reprogramming and membrane fatty acids synthesis.

Figure 4

Oncogenic Myc (red), Ras (violet), HIF-1 (blue), PI3K/AKT (green) which have common roles in metabolic reprogramming also increase cholesterol/lipid synthesis which may affect plasma membrane order altering membrane mediated signaling pathways.