Table 1.
Characteristics of studies included in meta-analysis (n = 18)
| Study (year) | Country | HCC patients (n/Mean age, yrs/male %) | Controls (n/Mean age, yrs/male %) | Cirrhosis (n/Mean age, yrs/male %) | Hepatitis (n/Mean age, yrs/male %) |
|---|---|---|---|---|---|
| Chau (2000) [22] | Taiwan | 67/63.4/89.6 | 27/–/– | – | – |
| Giannitrapani (2002) [16] | Italy | 87/62.2/68.9 | 28/55.4/67.8 | – | – |
| Coskun (2004) [30] | Turkey | 11/–/– | 12/–/– | – | – |
| Ataseven (2006) [31] | Turkey | 22/59.8/68.0 | 25/37.1/44 | 23/45.5/47 | – |
| Soresi (2006) [17] | Italy | 93/62.2/65.6 | 42/54.9/73.8 | 72/56.5/66.7 | – |
| Cheon (2007) [25] | Korea | 26/62.8/65.3 | 23/53.5/65.2 | – | – |
| Tangkijvanich (2007) [32] | Thailand | 70/55.0/85.7 | 10/–/– | – | – |
| Porta (2008) [18] | Italy | 30/Median: 62.3/70.0 | 30/matched/matched | 30/matched/matched | – |
| Wong (2009) [27] | China | 37/Median: 55.0/89.0 | – | – | 37/Median: 55.0/89.0 |
| El-Folly (2010) [19] | Egypt | 50/54.9/68.0 | 25/34.0/56.0 | – | – |
| Pang (2011) [28] | China | 32/–/– | 18/–/– | – | – |
| Chao (2012) [23] | Taiwan | 73/matched/matched | 30/matched/matched | – | – |
| Jang (2012) [26] | Korea | 110/58.6/71.8 | 24/–/– | – | – |
| Kao (2012) [24] | Taiwan | 47/60.1/80.9 | 139/43.9/56.8 | 57/52.9/82.5 | 291/43.8/63.2 |
| Metwaly (2012) [20] | Egypt | 40/57.6/77.5 | 15/50.7/73.3 | 31/53.7/83.9 | – |
| Othman (2013) [21] | Egypt | 20/–/60.0 | 20/–/50 | 20/–/75.0 | 20/–/65.0 |
| Tang (2013) [29] | China | 148/60.2/74.3 | 265/41.6/72.8 | 153/51.6/72.5 | 292/43.9/72.7 |
| Ohishi (2014) [33] | Japan | 224/66.4/60.7 | 644/63.7/60.1 | – | – |
HCC – hepatocellular carcinoma, n – number