Table 3.
Summary of Associations between the SNPs and ARC.
| Gene | SNPs Major/Minor |
Controls Major/Minor |
ARCs Major/Minor |
χ2 | P/Pa | OR (95%CI) |
|---|---|---|---|---|---|---|
| XPA | rs3176752 C/A |
1740/246 (12.4%) |
1751/235 (11.8%) |
0.286 | 0.592 | 0.95 (0.78-1.15) |
| XPC |
rs2229090
C/G |
1171/815 (41.3%) |
1305/681 (34.3%) |
19.255 | <0.001/<0.01 | 0.75 (0.66–0.85) |
| ATR | rs2241201 G/C |
1560/426 (21.5%) |
1553/433 (21.8%) |
0.073 | 0.787 | 1.02 (0.88–1.19) |
| rs877710 C/G |
1343/643 (32.4%) |
1306/680 (34.2%) |
1.552 | 0.213 | 1.09 (0.95–1.24) |
|
| rs11067231 C/A |
1350/636 (47.1%) |
1343/643 (32.4%) |
0.057 | 0.812 | 1.01 (0.89–1.16) |
|
| rs11067233 C/G |
1736/250 (12.6%) |
1726/260 (13.1%) |
0.225 | 0.635 | 1.05 (0.87–1.26) |
|
| RAD54 | rs7310449 A/G |
1191/795 (40.0%) |
1172/814 (41.0%) |
0.377 | 0.280 | 1.04 (0.92–1.18) |
| RAD55 | rs7301931 C/T |
1112/874 (44.0%) |
1096/890 (44.8%) |
0.261 | 0.316 | 1.03 (0.91–1.17) |
| XRCC4 | rs2035990 C/T |
1003/983 (49.5%) |
1015/971 (48.9%) |
0.145 | 0.364 | 0.98 (0.86–1.11) |
| XRCC5 | rs2440 C/T |
1589/397 (20.0%) |
1567/419 (21.1%) |
0.746 | 0.205 | 1.07 (0.92–1.25) |
Pa: P value after Bonferroni correction.