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. 2018 Oct 12;8:15185. doi: 10.1038/s41598-018-33407-w

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Gene expression in LPL and NPL groups at 60 and 90d. (A,C) Venn diagram showing genes only expressed in the LPL group (blue circle), only expressed in the NPL group (yellow circle), and common to both groups (intersection). (B,D) Different expressed genes between the LPL and NPL groups. The red points indicated significantly up-regulated expressed genes and the green points indicated significantly down-regulated expressed genes of LPL group. The blue points indicated that no significant difference of gene expression was found between the two groups.