Table 3.
Visceral Adipose Tissue | Subcutaneous Adipose Tissue | |||||
---|---|---|---|---|---|---|
Morbidly Obese | Ex-Morbidly Obese | p | Morbidly Obese | Ex-Morbidly Obese | p | |
Adipocyte Sizea | 167 (157–181) | 128 (118–135) | <0.001 | 185 (172–194)*** | 141 (127–155)## | <0.001 |
SVFb | 776 (469–1076) | 1905 (1315–3093) | <0.001 | 240 (137–471)*** | 296 (222–613)### | 0.035 |
Endothelial cells | 10.1 (7.2–19.3) | 28.8 (20.9–50.2) | <0.001 | 8.3 (5.1–14.4)* | 20.3 (12.1–28.5)## | <0.001 |
AdPCs | 155 (79–265) | 956 (687–1226) | <0.001 | 56 (32–121)*** | 203 (80–311)### | <0.001 |
Neutrophils | 221 (100–340) | 83 (13–238) | 0.021 | 36 (21–72)*** | 11 (6.4–19)### | <0.001 |
Macrophages | 82 (55–140) | 147 (82–303) | 0.053 | 30 (19–63)*** | 35 (15–80)### | 0.871 |
CD11c-Macrophages | 41 (22–58) | 40 (33–162) | 0.190 | 18 (11–38)*** | 10 (5.1–16)### | 0.003 |
% of CD11cc | 45.4 (30.5–59.1) | 35.6 (28.2–42.0) | 0.036 | 58.8 (45.5–70.0)*** | 32.0 (21.1–35.1) | <0.001 |
Mast cells | 9.9 (5.4–21) | 97 (56–120) | <0.001 | 6.3 (3.6–14.1)** | 25 (13–55)### | <0.001 |
T-Lymphocytes | 233 (132–356) | 379 (287–786) | <0.001 | 53 (28–94)*** | 60 (37–102)### | 0.370 |
T-helper | 97 (73–164) | 120 (83–259) | 0.342 | 31 (16–58)*** | 34 (22–52)## | 0.497 |
T-cytotoxic | 113 (48–161) | 211 (109–246) | 0.002 | 13 (92–27)*** | 17 (10–34)### | 0.386 |
% of T-cytotoxicd | 47.0 (36.7–51.1) | 59.9 (41.9–61.0) | 0.375 | 30.1 (25.2–34.9)*** | 32.2 (22.9–43.0)# | 0.428 |
B-Lymphocytes | 7.0 (2.9–13.0) | 4.4 (2.2–10.4) | 0.511 | 1.6 (0.7–3.7)*** | 1.2 (0.6–2.6)### | 0.500 |
Data are represented as median ± interquartile range. aAdipocyte size shows the mean of cell diameter in µm. bSVF was estimated by summing events positive for CD31, CD34 or CD45. cPercentage of the CD11c+phenotype within macrophages. dPercentage of T-cytotoxic phenotype within T-lymphocytes. The remaining variables show 103 cells/g of adipose tissue. ***P < 0.001, **P < 0.01, *P < 0.05 when comparing both types of adipose tissue in morbidly obese patients. ###P < 0.001, ##P < 0.01, #P < 0.05 when comparing both types of adipose tissue in ex-morbidly obese patients.