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. 2018 Oct 12;8:15183. doi: 10.1038/s41598-018-33636-z

Table 3.

Transmitted drug resistance mutation and confer resistance to ART drugs among the ART treatment naïve.

Samples PI SDRMs NRTI SDRMs NNRTI SDRMs Confer resistance to ART drugs
Manipur005 Y115F, M184V K103N, Y181C, G190A ABC (H), DDI (L), FTC (H), 3TC (H), EFV (H), ETR (I), NVP (I), RPV (H)
Manipur017 I54V, L76V, I84V K65R, M184V Y188L ABC (H), d4T (I), DDI (H), FTC (H), 3TC (H), TDF (I), EFV (H), ETR (L), NVP (H), RPV (H), ATV/r (H), DRV/r (I), FPV/r (H), IDV/r (H), LPV/r (H), NFV (H), SQV/r (H), TPV/r (I)
Manipur021 K219Q AZT (L), d4T (L)
Manipur034 K219Q AZT (L), d4T (L)
Manipur056 M184V, T215F Y181C ABC (L), AZT (I), d4T (I), DDI (L), FTC (H), 3TC (H), EFV (I), ETR (I), NVP (H), RPV (I)

SDRMs were analyzed by using the Calibrated Population Resistance (CPR) tool at HIV standard database (http://cpr.stanford.edu/cpr.cgi). SDRMs, surveillance drug resistance mutations; H, high; I, intermediate; L, low.