Table 3.
Samples | PI SDRMs | NRTI SDRMs | NNRTI SDRMs | Confer resistance to ART drugs |
---|---|---|---|---|
Manipur005 | — | Y115F, M184V | K103N, Y181C, G190A | ABC (H), DDI (L), FTC (H), 3TC (H), EFV (H), ETR (I), NVP (I), RPV (H) |
Manipur017 | I54V, L76V, I84V | K65R, M184V | Y188L | ABC (H), d4T (I), DDI (H), FTC (H), 3TC (H), TDF (I), EFV (H), ETR (L), NVP (H), RPV (H), ATV/r (H), DRV/r (I), FPV/r (H), IDV/r (H), LPV/r (H), NFV (H), SQV/r (H), TPV/r (I) |
Manipur021 | — | K219Q | — | AZT (L), d4T (L) |
Manipur034 | — | K219Q | — | AZT (L), d4T (L) |
Manipur056 | — | M184V, T215F | Y181C | ABC (L), AZT (I), d4T (I), DDI (L), FTC (H), 3TC (H), EFV (I), ETR (I), NVP (H), RPV (I) |
SDRMs were analyzed by using the Calibrated Population Resistance (CPR) tool at HIV standard database (http://cpr.stanford.edu/cpr.cgi). SDRMs, surveillance drug resistance mutations; H, high; I, intermediate; L, low.