Figure 7.

Liver iron content and hepcidin expression are not different between WT and Erfe ^−/− mice under basal conditions or after chronic EPO treatment. (A) Serum hepcidin concentrations in WT and Erfe ^−/− mice chronically treated with either EPO or saline (NaCl). Groups were analyzed by three‐way ANOVA (genotype, sex, treatment), and there was no significant interaction between factors (P < 0.05). (B) Liver nonheme iron concentrations in WT and Erfe ^−/− mice chronically treated with either EPO or saline (NaCl). Groups without a common alphabetical superscript differ significantly from other groups of the same sex as determined by one‐way ANOVA (P < 0.05). Data are shown as the mean ± SEM (n = 5–7 per group for each sex).