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Abcb1a promoter region analysis. Shown are the Abcb1a loci of wild-type and hABCB1 mice in comparison. ENCODE database searches revealed the indicated hotspots of open/accessible chromatin found in mouse brains using DNAse-seq, ATAC-seq, and ChIP-seq methods. The area of highest density of overlapping hotspots (orange/light orange) covers more than 200 bp indicating the importance of this region for Abcb1a gene expression.
