Table 3.
Comparison of MRND type and clinicopathologic characteristics
| Variables | Ipsilateral MRND | Bilateral MRND | p |
|---|---|---|---|
| N = 346 | N = 44 | ||
| Age | 46.2 ± 13.3 | 48.1 ± 15.6 | 0.369 |
| ≤ 55 years | 255 (73.7) | 30 (68.2) | 0.471 |
| > 55 years | 91 (26.3) | 14 (31.8) | |
| Sex | < 0.001 | ||
| Female | 252 (72.8) | 20 (45.5) | |
| Male | 94 (27.2) | 24 (54.5) | |
| Main tumor size (cm) | 1.54 ± 0.91 | 2.20 ± 1.21 | < 0.001 |
| ≤ 2 cm | 272 (78.6) | 25 (56.8) | 0.002 |
| > 2 cm | 74 (21.4) | 19 (43.2) | |
| Number of central lymph node | |||
| Harvested | 7.2 ± 5.9 | 8.4 ± 6.2 | 0.210 |
| Metastatic | 3.4 ± 3.5 | 6.3 ± 6.0 | < 0.001 |
| Number of lateral lymph node | < 0.001 | ||
| Harvested | 16.6 ± 8.1 | 33.6 ± 13.3 | < 0.001 |
| Metastatic | 4.2 ± 2.9 | 10.5 ± 5.5 | |
| Skip metastases | 80 (23.1) | 6 (13.6) | 0.179 |
| LN ratio | 0.34 ± 0.19 | 0.41 ± 0.21 | 0.012 |
| Multifocality | 114 (32.9) | 28 (63.6) | < 0.001 |
| Bilaterality | 101 (29.2) | 24 (54.5) | 0.001 |
| ETE | 0.003 | ||
| No/minor | 252 (72.8) | 22 (50.0) | |
| Gross | 94 (27.2) | 22 (50.0) | |
| CLT | 92 (26.6) | 8 (18.2) | 0.274 |
| LVI | 16 (4.6) | 4 (9.1) | 0.263 |
| Stage | 0.406 | ||
| I | 255 (73.7) | 30 (68.2) | |
| II | 70 (20.2) | 9 (20.5) | |
| III | 21 (6.1) | 5 (11.4) | |
| Recurrence | 67 (19.4) | 17 (38.6) | 0.006 |
MRND modified lateral neck dissection, LN lymph node, ETE extrathyroidal extension, CLT chronic lymphocytic thyroiditis, LVI lymphovascular invasion