Table 1.

Model evaluation by LSSA and microarray analysis of mesothelioma cell line Mero-14

Source scenario in Mero-14	Target scenario in Mero-14	LSSA simulation	Total number of genes	Number of correct predictions	p-value of correct predictions	Number of small error predictions	Number of large error predictions
TP53 wt without treatment	TP53 wt with Gem treatment	TP53 wt with DNA damage ON vs TP53 wt with DNA damage OFF	199	149 (74.87%)	4.33 × 10−33	48 (24.12%)	2 (1.01%)
TP53 wt without treatment	TP53 wt with etoposide treatment	TP53 wt with DNA damage ON vs TP53 wt with DNA damage OFF	199	142 (71.36%)	5.88 × 10−28	56 (28.14%)	1 (0.5%)