Table 4.
Correlation of genes and processes with survival of mesothelioma patients; the Pearson correlation coefficient is shown
| TP53 WT T | TP53 WT UT | TP53 MUT UT | |||
|---|---|---|---|---|---|
| Gene | Survival correlation | Gene | Survival correlation | Gene | Survival correlation |
| CKB | 0.495 | DDIT4 | − 0.507 | E2F1 | − 0.498 |
| MUC1 | − 0.510 | MMP2 | − 0.521 | FOXM1 | − 0.504 |
| FOXM1 | − 0.519 | NLRC4 | − 0.508 | ||
| E2F1 | − 0.526 | CDC20 | − 0.512 | ||
| SFN | − 0.530 | AURKA | − 0.515 | ||
| CKS2 | − 0.533 | RAS | − 0.518 | ||
| CHEK1 | − 0.534 | PLAUR | − 0.519 | ||
| HSP90AB1 | − 0.535 | MCTS1 | − 0.522 | ||
| RECQL4 | − 0.535 | GAPDH | − 0.523 | ||
| PTTG1 | − 0.539 | EZH2 | − 0.534 | ||
| AURKA | − 0.559 | ECT2 | − 0.548 | ||
| PRC1 | − 0.563 | PRC1 | − 0.561 | ||
| HMMR | − 0.575 | APAF1 | − 0.566 | ||
| FEN1 | − 0.582 | BRCA1 | − 0.579 | ||
| HSP90AB1 | − 0.583 | ||||
| NCL | − 0.604 | ||||
| MAPK14 | − 0.611 | ||||
| HIF1A | − 0.624 | ||||
| SIAH1 | − 0.702 | ||||
Patients treated by chemotherapy are indicated by T; patients untreated by chemotherapy are indicated by UT. Wild type p53 status is labelled WT and mutant is labelled MUT