Table 5.

Univariate Cox regression analysis

Gene name	Beta coefficient	Hazard ratio (95% confidence interval for HR)	p value
CKB	− 0.0621	0.97 (0.819–1.08)	0.376
MUC1	0.181	1.2 (0.944–1.47)	0.0566
FOXM1	0.462	1.59 (1.28–1.96)	1.89E−05
E2F1	0.143	1.15 (1.06–1.25)	0.000551
SFN	0.0768	1.08 (0.983–1.19)	0.111
CKS2	0.408	1.5 (1.19–1.91)	0.000783
CHEK1	0.55	1.73 (1.3–2.31)	0.000165
HSP90AB1	0.494	1.64 (1.25–2.16)	0.000412
RECQL4	0.442	1.56 (1.25–1.94)	8.71E−05
PTTG1	0.397	1.49 (1.18–1.88)	0.000819
AURKA	0.438	1.55 (1.25–1.93)	8.47E−05
PRC1	0.435	1.54 (1.27–1.88)	1.31E−05
HMMR	0.355	1.43 (1.18–1.73)	0.00029
FEN1	0.345	1.41 (1.05–1.91)	0.024
DDIT4	0.348	1.42 (1.16–1.73)	0.000689
MMP2	0.14	1.15 (1.06–1.24)	0.000414
NLRC4	0.109	1.12 (0.844–1.47)	0.443
CDC20	0.361	1.43 (1.21–1.71)	4.61E−05
RAS	0.32	1.38 (1.11–1.71)	0.0039
PLAUR	0.185	1.2 (0.98–1.48)	0.0779
MCTS1	0.542	1.72 (1.09–2.71)	0.0194
GAPDH	0.119	1.13 (0.86–1.47)	0.388
ECT2	0.49	1.63 (1.3–2.04)	1.87E−05
EZH2	0.184	1.2 (1.09–1.33)	0.000268
APAF1	0.443	1.56 (1.15–2.1)	0.00383
BRCA1	0.203	1.22 (1.11–1.35)	6.32E−05
HIF1A	0.146	1.16 (1.01–1.33)	0.0404
MAPK14	0.139	1.15 (0.803–1.64)	0.447
NCL	0.504	1.66 (1.13–2.43)	0.00978
SIAH1	0.143	1.15 (0.974–1.37)	0.0986

The Cox regression results for genes listed in the Table 4 are shown in the Table 5. The column of beta coefficient shows the beta regression coefficient. The column of HR [95% confidence intervals (CI) for HR] list the hazard ratios (the exponentiated coefficients) and the size of the confidence intervals of the hazard ratios. The column of p value lists the p value for the Wald test method