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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Nitric Oxide. 2018 Aug 9;80:108–112. doi: 10.1016/j.niox.2018.08.003

Figure 1: Primary cilia structure.

Figure 1:

The axoneme of primary cilia is mainly anchored from the basal body and enclosed within the ciliary membrane which is continuous with the plasma membrane. The basal body is composed of the mother and the daughter centrioles and some transition fibers to anchor the basal body to the cell membrane. The ciliary membrane hosts specific membrane and protein receptors that facilitate proper cilia signaling (Left panel). Primary cilia found on the surface of vascular endothelial cells can be identified by a simple immunofluorescence technique utilizing antibody against acetylated α-tubulin (green) to label primary cilia and pericentrin (red) to label centriole or basal body. The nucleus is counterstained with DAPI to label DNA (Right panel). Left panel is adopted from [73].