Figure 6.

Effect of CAPE on activation and expression of AMPK, ACC, and LKB1 in wild type mouse brain. Normal control mice were treated iv with either 5mg/kg CAPE in 50% DMSO or 50% DMSO alone. The animals were sacrificed 2 h after the injection and the expressions of pAMPK and AMPK with densitometry (A, A1); pACC and ACC with densitometry (B, B1); and pLKB1 and LKB1 with densitometry (C, C1) in cortical area were determined using western blot analysis. Data are presented as mean ± SD (n=4). ***p<0.001, **p<0.01 vs. DMSO.