Table 2.
Leukapheresis collection and product data
Fresenius Com.Tec | Spectra Optia | p value | |
---|---|---|---|
Number of collection (n) | 64 | 126 | p = 0.11 |
Age at collection | 50.1 ± 14.6 | 49.6 ± 13.5 | p = 0.08 |
Weight at collection (kg) | 74.9 ± 12 | 73.7 ± 16 | p = 0.94 |
Number of apheresis per case | 2 ± 1 | 2 ± 1 | p = 0.06 |
ACD used (mL)* | 564 ± 118 | 802 ± 207 | p = 0.001 |
Total blood volume (mL)* | 4.1 ± 0.9 | 2.1 ± 0.4 | p = 0.001 |
Processed blood volume (L)* | 7.6 ± 1.4 | 10.5 ± 1.1 | p = 0.04 |
Plasma volume (mL) | 103 ± 28 | 98 ± 28 | p = 0.22 |
Product volume (mL)* | 231 ± 58 | 185 ± 61 | p = 0.039 |
Collection time (min)* | 171 ± 30 | 226 ± 37 | p = 0.01 |
Product WBC × 103 (µL)* | 215 (60–500) | 232 (60–570) | p = 0.027 |
Product Hct (%)* | 0.61% (0.3–3.6%) | 1.24% (0.3–3.1%) | p = 0.001 |
Peripheral CD34+ cell count (µL) | 52 ± 36 | 48 ± 53 | p = 0.13 |
CD34+ cell count in Product (µL)* | 1105 ± 1164 | 1576 ± 1475 | p = 0.01 |
CD34+ cells infused (106/kg) | 3.2 ± 3.7 | 3.75 ± 3.7 | p = 0.41 |
CD34+ collection efficiency 2 (CE2) %* | 70% (3–200%) | 87% (6–390%) | p = 0.033 |
*p < 0.05 is significant