Table 1.
Demographic and clinical characteristics of recruited patients
| PCOS-IR n=20 | PCOS-IS n=20 | Control n=20 | P value | |
|---|---|---|---|---|
| Age (Y) | 30.04 ± 4.45 | 28.00 ± 4.00 | 29.05 ± 5.18 | 0.381 |
| Previous ART | ||||
| Yes | 7 (25.9) | 7 (25.9) | 13 (48.2) | 0.108 |
| No | 15 (42.9) | 12 (34.3) | 8 (22.8) | |
| Fasting insulin (mg/dl) | 19.30 ± 9.60 | 6.67 ± 2.89 | - | 0.006 |
| BMI | 29.97 ± 4.39a | 26.31 ± 8.03ab | 25.12 ± 4.21b | 0.023 |
| Oocyte retrievedMIIMIGVDegenerated/dead | 11.90 ± 7.098.01 ± 3.61a0 (0-3; 1)0 (0-2; 0)0 (0-1; 0) | 13.58 ± 11.269.05 ± 3.37ab0 (0-2; 0)0 (0-4; 1)0 (0-4; 1) | 12.90 ± 5.59111.57 ± 5.11b0 (0-1; 1)0 (0-3; 1)0 (0-2; 0.5) | 0.8140.0280.8060.4680.125 |
| Total embryo | 7.15 ± 4.29 | 9.44 ± 7.34 | 7.95 ± 4.07 | 0.415 |
| 2PN embryos | 6 (0-14; 4.75) | 7 (1-13; 3.25) | 9 (2-18; 4.5) | 0.723 |
| Fertilization (%) | 73.28 ± 25.43 | 75.90 ± 25.89 | 76.01 ± 17.24 | 0.914 |
PCOS; Polycystic ovary syndrome, IR; Insulin resistant, IS; Insulin sensitive, ART; Assisted reproductive technology, BMI; Body mass index, MI; Metaphase I oocytes, MII; Metaphase II oocytes, GV; Germinal vesicle stage, 2PN; Two pronuclei. Continuous variables are presented as mean ± SD or median (minimum-maximum; inter-quartile range) when appropriate. Categorical variables are presented as number (%). Different letters indicate significantly different means (as evaluated by ANOVA and Tukey post-hoc test). A P<0.05 was considered significant.