Table 2.
Univariate and multivariate predictors of all-cause mortality among 224 patients of the BNP- and echo-guided group.
| Variable | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR (95% CI) | p-value | HR (95% CI) | p-value | |
| Age | 1.03 (1.00, 1.05) | 0.043 | ||
| Male | 0.98 (0.51, 1.97) | 0.98 | ||
| Heart rate | 1.01 (1.00, 1.03) | 0.11 | ||
| Ischemic CM | 1.23 (0.88, 1.72) | 0.29 | ||
| Diabetes | 1.98 (1.13, 3.45) | 0.021 | ||
| Hypertension | 0.97 (0.55, 1.73) | 0.93 | ||
| Atrial fibrillation | 1.39 (0.68, 2.85) | 0.38 | ||
| NYHA class | 2.38 (1.67, 3.38) | <0.0001 | ||
| Systolic BP | 0.97 (0.95, 0.99) | 0.0022 | ||
| Diastolic BP | 0.96 (0.93, 0.99) | 0.0032 | ||
| eGFR | 0.98 (0.97, 0.99) | 0.0040 | ||
| BNP | 1.00 (1.00, 1.00) | <0.0001 | ||
| BNP >125 pg/ml or decrease ≤30% | 5.74 (2.97, 11.07) | <0.0001 | 1.55 (1.35, 1.77) | 0.0038 |
| LVEF | 0.89 (0.85, 0.92) | <0.0001 | 0.94 (0.89, 1.00) | 0.051 |
| Mitral regurgitation | 3.58 (3.00, 6.38) | <0.0001 | ||
| EDT | 0.99 (0.98, 0.99) | <0.0001 | ||
| E/e′ averaged | 1.06 (1.04, 1.08) | <0.0001 | 1.05 (1.02, 1.08) | 0.0054 |
| B-lines ≥ 15 | 7.32 (4.13, 12.96) | <0.0001 | ||
HR: hazard ratio. For other abbreviations, see Table 1.