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A. Bioluminescence imaging of Ovcar8-IP tumors. Tumors treated with cisplatin emit noticeably weaker signal than siTWIST or siQ only control mice, while those treated with siTWIST-MSNs plus cisplatin exhibit a further loss of signal. siTWIST-MSN-HAs plus cisplatin exhibit a greatest loss of signal. B. Quantification of bioluminescence for all seven weeks of treatment as depicted in A for weeks 1 and 7. Units for luminescence are photons/sec/cm2/steradian.
