Table 2.
Logistic regression model for any local treatment complication*
| Variable | RR (95% CI) | P |
|---|---|---|
| Local therapy | ||
| Lump+WBI | 1 (Ref) | |
| Lump+Brachy | 1.43 (1.38 to 1.49) | <.001 |
| Lump alone | 1.07 (1.01 to 1.14) | .01 |
| Mast alone | 1.03 (1.00 to 1.07) | .09 |
| Mast+Recon | 1.79 (1.75 to 1.83) | <.001 |
| Age, y | ||
| <40 | 1 (Ref) | |
| 40–49 | 1.02 (.96 to 1.09) | .42 |
| 50–59 | 1.03 (.97 to 1.08) | .37 |
| 60–64 | 1.04 (.98 to 1.10) | .24 |
| Comorbidity | ||
| 0 | 1 (Ref) | |
| 1 | 1.25 (1.20 to 1.30) | <.001 |
| 2 or higher | 1.37 (1.26 to 1.48) | <.001 |
| Chemotherapy | ||
| None | 1 (Ref) | |
| Without trastuzumab | 1.09 (1.06 to 1.12) | <.001 |
| With trastuzumab | 1.15 (1.09 to 1.21) | <.001 |
*No patients were excluded. RR = relative risk; CI = confidence interval; Brachy = brachytherapy; Lump = lumpectomy; Mast = mastectomy; Recon = reconstruction; WBI = whole breast irradiation. All P values were two=sided and calculated in the logistic regression models.