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. 2018 Jul 16;110(10):1148–1152. doi: 10.1093/jnci/djy135

Table 3.

Unadjusted and Adjusted 2-year Costs by Local Therapy Strategy, Diagnosis years 2010-2011*

Unadjusted costs, $
Adjusted costs, $
Total
Complication Noncomplication
Total Complication Noncomplication
Treatment Mean (95% CI) Median (IQR) Mean (95% CI) Mean (95% CI) Median (IQR) Mean (95% CI) Mean (95% CI) Mean (95% CI)
Lump+WBI 77 314 (75 772 to 78 856) 60 266 (41 228 to 93 905) 1358 (1205 to 1511) 75 883 (74 367 to 77 401) 59 210 (40 374 to 91 950) 68 841 (67 622 to 70 061) 1336 (1193 to 1479) 67 225 (66 043 to 68 407)
Lump+Brachy 72 184 (68 637 to 75 732) 60 339 (39 424 to 89 279) 1631 (1241 to 2021) 70 467 (66 970 to 73 963) 58 805 (38 340 to 87 453) 80 299 (76 554 to 84 045) 1672 (1201 to 2142) 78 621 (74 983 to 82 259)
Lump alone 63 860 (56 672 to 71 048) 53 996 (23 984 to 86 311) 2493 (1676 to 3310) 60 183 (53 012 to 67 354) 46 983 (20 166 to 81 777) 76 313 (69 803 to 82 823) 2604 (1476 to 3732) 73 595 (67 368 to 79 823)
Mast alone 62 229 (58 855 to 65 602) 40 203 (21 332 to 81 796) 2630 (1826 to 3434) 59 481 (56 294 to 62 668) 38 278 (20 193 to 78 658) 52 586 (50 749 to 54 423) 2489 (1960 to 3018) 50 081 (48 351 to 51 812)
Mast+Recon 96 010 (93 569 to 98 451) 75 725 (49 456 to 117 680) 9552 (8759 to 10 345) 85 956 (83 687 to 88 225) 66 404 (43 117 to 105 221) 90 986 (88 925 to 93 046) 9708 (8401 to 11 017) 80 187 (78 379 to 81 995)
*

Adjusted costs are adjusted for the variables listed in Table 1. Each cost model was iteratively refined to remove covariables that did not statistically significantly contribute to the model. No patients were excluded from any calculation. All figures are reported in 2014 dollars. Brachy = brachytherapy; CI = confidence interval; Lump = lumpectomy; Mast = mastectomy; Recon = reconstruction; WBI = whole breast irradiation.